Project:
Leukocyte, specifically macrophage, behavior, in atherosclerosis and renal disease are altered in several regards (Ge et al., Circulation Research 2013, PMID: 23908345). We currently investigate the mechanisms how uremic toxins alter vascular inflammation with funding from DFG and Else-Kroener Fresenius-Stiftung. The new PhD project will employ animal experiments (organ preparation and analysis by histology including microscopy and multi-color flow cytometry) and complimentary work with human leukocytes and tissue samples to address macrophage function in uremia.
Recent related publications:
Ge et al., Circulation Research 2013, PlosOne 2014, von Vietinghoff et al, JACC 2011
Your profile:
You hold a medical or veterinary degree or Master’s Degree/Diploma in biology, biochemistry, pharmacy, or a related field of the life sciences, and are highly motivated to work responsibly in a translational project involving both clinicians and basic scientists. Animal work is a central part of the project, a completed FELASA certification is preferred but not required at start. Previous experience with immunologic techniques such as confocal microscopy and flow cytometry is very welcome.
Planned starting date: February 2015
Initial contract for 2 years with possible extension (Probation period: 6 months)
Salary: TVöD E13 (65%)
Please send your application as a single PDF file including: CV, publication list together with a short sketch of your research interests and the names of two academic referees to vonVietinghoff.Sibylle@mh-
