The research of the Robatzek laboratory aims at discovering important mechanisms of subcellular transport processes that are reprogrammed upon pathogen infection. To identify mechanistic and functional elements of pathogen-reprogrammed subcellular transport, we focus on the dynamic localization of the pattern recognition receptors (PRRs), the primary sensors of the plant’s immune system. This has led us to several novel findings linking transport processes involved in defence and PRR trafficking: Regulation of immunity by cellular transport (Spallek et al. 2013), pathogen-induced modulation of PRR abundance (Göhre et al. 2008), trafficking that differentially localizes PRRs to the host-pathogen interface (Lu et al. 2012), and activation-dependent endosomal transport of PRRs (Beck et al. 2012; Spallek et al. 2013).
The postdoctoral researcher will be studying the pathogen-induced and -inhibited endocytosis across PRRs families by biochemical and molecular approaches combined with confocal imaging.
The Sainsbury Laboratory, a world leader in plant and microbial science, is a charitable company of ~100 research scientists and support staff. We are based on the Norwich Research Park and have close links with the John Innes Centre, The Genome Analysis Centre and the University of East Anglia.
For more information visit www.tsl.ac.uk and www.robatzek.ac.uk
The group of Silke Robatzek, currently located at the Sainsbury Laboratory, Norwich, and is looking for a postdoctoral researcher starting autumn 2015. The postdoctoral researcher is expected to have a strong background in modern cell biology and biochemistry. Experience in plant-microbe interactions is a benefit. A suitable background is PhD in biochemistry and cell biology. For further information please contact Dr. Hannah Kuhn (Hannah-Kuhn@TSL.ac.uk). This is a 24 months position.
Salary will be within the UEA Research & Analogous staff Grade 7, at between £31,342 and £37,394 per annum and the appointment level will reflect the qualifications, skills, knowledge and achievements of the successful candidate.
Applicants should provide a CV, including the names and contact details of two referees, and a covering letter addressing the selection criteria. Applications may be submitted online using the ‘Apply’ button below. Alternatively applications may be submitted by e-mail to HR@TSL.ac.uk or by post to Kim Blanchflower, HR Manager, The Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, UK. Please quote the reference SR10/2015 if applying by email or post.
Ref NUMBER SR10/2015 Closing Date 19 July 2015
13 de julio de 2015
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Postdoc in Pathogen-Reprogrammed Subcellular Transport (Norwich, UK)