Job description
The proposed project addresses the formation and function of the spinal locomotor network in zebrafish. The goal is to connect the formation of the circuit with its functionality, both at the cellular and at the organism level. In vivo time-lapse imaging of fluorescent reporter lines should reveal how cells are generated and integrated within the locomotor circuitry. State-of-the-art techniques, such as optogenetics and genetically encoded calcium indicators, will help to define the functional role of interneuron populations in zebrafish and mice spinal microcircuits. The work will be performed within the unit of Developmental Genetics that consists of four PI's who will contribute with their expertise during various aspects of the project (http://www.neuro.uu.se/research/developmental+genetics/).Candidates should have a PhD degree with a robust background in neuroscience. Applicants should have demonstrated outstanding performance throughout their previous studies with their own publications. The candidate should be highly motivated, organized, and able to work independently. Strong English skills are also important.
Candidates should have experience in at least two of the following:
1) Zebrafish or mouse as a model system
2) Optogenetics in neural tissue
3) Neural calcium imaging
4) Long-term live imaging
5) Electrophysiology
The position is available immediately, with stipend-based funding for 1 year with the possibility of extension.
How to apply
Interested candidates should send their applications; cover letter including a brief statement of research interests and technical expertise, CV, publication list, a letter of recommendation as well as contact details of one additional reference directly to Dr. Boije (henrik.boije@neuro.uu.se).
Contact details
Contact person: Henrik Boije (henrik.boije@neuro.uu.se)
http://www.neuro.uu.se/research/developmental+genetics/zebrafish-neural-networks/