Job Description
The position involves the management of all activities related to the functional characterization of the products produced by Curaxys. These operations include the team training management, the documentation of all reports generated during the characterisation process, the monitoring and assessment of the quality control and the observation of the GMP standard working procedures. Suitable candidates woud possess the experience and knowledge of the following techniques:
Management and control tests required for functional characterisation assays of products produced by Curaxys
Skills in the following molecular and cellular biology techniques:
- Prokaryotic- and Mammalian cell culture
- Electrophoresis: SDS-PAGE (1-D, 2-D), Western-Blot
- Protein quantification: Bradford, ELISA.
- Fluorescence microscopy.
- PCR and qPCR
- Gel documentation and analysis system
- Sonication
- Experience in development of binding assays:
- Affinity
- Inmunoreactivity
- Avidity
- Experience in development of activity assays
- ADCC
- CDC
- Optimisation of medium culture.
- Flow cytometry.
- Purification techniques (affinity, ion exchange, size exclusion chromatography) with FPLC
- Demonstrable leadership skills, ability to manage, supervise and coordinate a department team
- Working according to GMP standards
- Maintenance and redaction of Standard Operating Procedures
Qualifications
Researchers with a PhD or MSc degree in Chemistry, Biochemistry, Biology, Pharmacy or Chemistry Engineering, with a minimum average qualification of 1.7 will be considered suitable candidates. English fluency is a key issue and must be demonstrated.
